Towards early detection of retinoblastoma

Bilateral retinoblastoma in early infancy.

INTRODUCTION Retinoblastoma is the most common primary intraocular malignancy of childhood. It is usually diagnosed before the age of 5 years. In spite of its early onset in most children, retinoblastoma is rarely diagnosed congenitally or even within the first 3 months of life. OBJECTIVE To report a case of retinoblastoma in early infancy. CASE This was a case of the earliest presentation ...

Importance of early diagnosis of retinoblastoma.

A rapid, early detection of oral squamous cell carcinoma: Real time PCR based detection of tetranectin

The current study is focused on determining the mRNA expression levels of tetranectin, to detect oral squamous cell carcinoma (OSCC) and thus aiding in its classification at an early stage. RNA was isolated and cDNA synthesis was performed from the saliva samples of the patients and healthy individuals. A semiquantitative PCR based analysis was performed prior to quantitative and expression bas...

Towards early detection of pulmonary hypertension: a call to arms.

On average, even in the current era, patients have been symptomatic for .2 years by the time the diagnosis of pulmonary hypertension is made [3, 4]. If our understanding of the pathobiology of PAH is correct, then by the time of diagnosis, there will have been extensive remodelling and/or obliteration of a very significant proportion of the small muscular pulmonary arteries in our patients. The...

Towards a Classifcation of Tree Health and Early Detection

Forty-¤ ve green ash (Fraxinus pennsylvanica) street trees in Toledo, Ohio were photographed, measured, and visually rated for conditions related to emerald ash borer (Agrilus planipennis)(EAB) attacks.  ese trees were later removed, and sections were examined from each tree to determine the length of time that growth rates had been impacted. A classi¤ cation system was developed to discern th...